This is a sub for professional veterinary advice, and as such we follow strict rules for participating. Although commonly thought to be innocuous to both the research animals and any transgenic elements that the animals may carry . 2008;19(1):26-27. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. The expiration date reads September 2019. Table salt, kosher salt or sea salt, will stay as fresh as the day you bought it and remain so throughout the years. What if I administer more than the prescribed amount of Revolution to my dog or cat? Dogs that are homozygous for the ABCB1-1 mutation therefore cannot be treated with extra-label doses of ivermectin, as may be used for conditions such as demodectic mange. Selamectin as a sole agent did not affect I scapularis and provided only some efficacy against D variabilis.19. This medication should take effect within 4 to 8 hours, and will reach full effectiveness within the first week. Revolution has been tested safe in over 100 different pure and mixed breeds of healthy dogs and over 15 different pure and mixed breeds of healthy cats, including pregnant and lactating females, breeding males and females, puppies six weeks of age and older, kittens eight weeks of age and older, and avermectin-sensitive collies. Avoid contact with human skin; if it occurs, wash the skin immediately and thoroughly. Though I'd never heard of this law, it seems pharmacists are required to attach a one-year expiration date to all of the drugs they dispense. They must be exposed to Revolution on your dog or cat before being killed. Once you've applied it, Revolution is quickly absorbed into your pet's bloodstream, killing heartworm and in cats, even intestinal worms. Revolution is also used on dogs for the treatment or prevention of the American Dog Tick, and canine sarcoptic mange. I do believe the people at the vet's office honestly believe that Revolution is a safer alternative. This summary contains important information about Revolution. Vet Parasitol. Does it specifically state it's the expiry date. This long-acting medication may last up to 4 6 weeks, and may last longer in pets with kidney or liver disease. If you've been slack with that then you're best not using revolution and get a flea only product before getting a heartworm test on the dog. Symptoms beyond these (such as drooling, rapid breathing, lack of coordination, vomiting, or diarrhea) could be due to shock as a result of selamectin killing heartworms or other vulnerable parasites present at high levels in the bloodstreams of dogs. fleas and heartworm Log in 24/7 to access your pets health care information. The obstacle does not lie with product availability, as there are many commercially available preventive options; rather, as with ticks, many owners assume that their indoor-only cat is not susceptible and simply opt out or forget to treat their cat. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. The efficacy of a topical formulation of selamectin plus sarolaner in preventing the development of a macrocyclic lactone-resistant strain of, Animal Medicinal Drug Use Clarification Act. The medicine absorbs into the pet's skin and enters its circulatory system so that any biting insects die instantly. The world is changing, and keeping that thought in mind, we at BudgetVetCare, thought of doing something different. Skin diseases in companion guinea pigs (Cavia porcellus): a retrospective study of 293 cases seen at the Veterinary Medical Teaching Hospital, University of California at Davis (1990-2015). October 31, 2019 November 4, 2019 budgetvetcare can i give my dog expired nexgard, can i use expired revolution for cats, can you use expired flea medicine, does advantage flea medicine expire, does expired nexgard still work, expiration date on flea medicine, is expired nexgard safe, is it ok to give a dog expired medicine, out of date flea . And get this they're legally enjoined to do so regardless of the manufacturer's expiration dates. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some animals. Zoetis. You may occasionally see a few fleas on dogs or cats treated with Revolution but more than 98% of adult fleas are killed within 36 hours. Textbooks and formularies may advocate particular products for flea control in rabbits; however, veterinarians must realize there is very little in the literature regarding actual pharmacokinetics and safety. 3. Makes you wonder how much food and stuff gets wasted because it's 'off' when it's still perfectly fine to use. Imitation vanilla does not have the same life span. Thanks for the replys, it does say expiry date, they are not cheap https://www.budgetpetproducts.com.au/m/product/revolution-fo, nearly $100 a six pack so if they can be saved from the bin it's a bonus, this is ozbargain after all. And it's not consumer friendly. Our BudgetVetCare rep sat down and got together with a well-reputed veterinarian and churned out valuable information about a very important topic called Flea and Tick Treatments and Expiration Dates! In dogs, seizures and incoordination have been rarely reported. 2. and prevent and control If it was previously clear and it is now cloudy even if it has NOT expired Id question the stability of this medication. We have got you covered. I don't know about that product specifically, but I've spoken to Bayer Cropscience technical team (who make dog products and other pesticides) and they have said their pesticides will still be effective for at least 2 years after expiry. Package insert / product label Washington State University Veterinary Clinical Pharmacology Laboratory. 14. Revolution contains the active ingredient selamectin (a semisynthetic avermectin), which controls endoparasites and ectoparasites, including adult fleas, flea eggs, ticks, heartworms, ear mites, and sarcoptic mange in dogs, for 30 days. For the treatment and control of intestinal hookworm (A. tubaeforme) and roundworm (T. cati) infections, Revolution should be applied once as a single topical dose. Monthly use of Revolution will control any subsequent sarcoptic mange mite infestations. Acta Vet Scand. Revolution may be administered year-round or at least within one month after the animal's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. Most will have a longer shelf life if they are refrigerated. Revolution is available in eight separate dose strengths for dogs and cats of different weights. Comparative efficacy of topical treatments with Revolution Plus (selamectin and sarolaner) and Bravecto for Cats (fluralaner) against Ixodes scapularis ticks on cats. It is indicated for sarcoptic mange and the prevention of American dog tick infestation in dogs. Just think of the welfare of the animals involved, chuck out the expired stuff or give it to your local pet-shelter / let their qualified vet make the decision as to which animals it should be used on (don't 'sell it on' on GumTree to be used on some other poor animal; for what, at best a few dollars in your pocket? Revolt (selamectin) is a highly affordable, once-a-month prevention answer for heartworms, fleas, and a host of other problematic parasites. McTier TL, Shanks DJ, Watson P, et al. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly onto the skin in one spot. Efficacy of selamectin against experimentally induced and naturally acquired infections of, 12. In safety studies, Revolution was administered at 1, 3, 5, and 10 times the recommended dose to six-week-old puppies, and no adverse reactions were observed. At the discretion of the veterinarian, cats 6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with Revolution. Your veterinarian will recommend the appropriate dose for your dog or cat based on your animal's body weight. Cats are also notoriously difficult to medicate (whether via oral or topical route), and many owners may balk at the idea of a regularly scheduled medication administration date with their cat. For myself and my own family, that is. This last is the part that can be hard to determine with many products. Results of clinical field studies using Revolution monthly demonstrated >90% control of flea infestations within 30 days of the first dose. What To Do With Expired Medications . Be sure to keep away from extreme heat or an open flame as this medication is flammable. Hello everyone :) I was just cleaning out a cabinet and found a full pack of Revolution for cats. Ivermectin and selamectin are common oral and topical treatments for these infections, respectively. That's my take, anyway. So why make them come in again for a "fresh" round? To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Revolution is not for use in humans. The following medications should be used with caution in dogs with the MDR1 genetic mutation when given with selamectin: amiodarone, carvedilol, clarithromycin, cyclosporine, diltiazem, erythromycin, itraconazole, ketoconazole, quinidine, spironolactone, tamoxifen, and verapamil. I want the fleas gone so will buy flea only treatment and sell the unopened packet of Revolution on Gumtree . In humans, Revolution may be irritating to skin and eyes. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 16. As always, veterinarians using drugs in an extra-label manner must adhere to the FDA requirements as set forth by the. Yes, if your cat is 10lb, you can use two of the 2.8-5.5 lb doses of Revolution Plus. Should I toss this, or can it still be used? Sincerely, Do not apply to broken skin Revolution contains alcohol. Revolt Topical offers the same exact active ingredient and mode of action as the pioneer product, but at greatly reduced pricing. With this in mind, you might want to opt for the slightly more expensive vanilla without an expiration date. Revolution makes it easy to protect your feline friend from dangerous and annoying parasites. Immature stages of the flea called pupae may be present in your pets' environment (yard, flooring, carpet, bedding, etc.). In one easy-to-administer monthly dose, it provides protection against five parasites:*. Other concentrations are also available, but those are recommended for use in dogs. Same for lots of human medicines, which are often shipped to third world countries once they go past expiry dates as well as bandages and what not. Hill WA, Brown JP. 2000;91(3-4):233-250. This monthly spot-on solution controls and prevents deadly heartworm infections. For a copy of the MSDS or to report adverse reactions attributable to exposure to this product, call 1-800-366-5288. If your dog doesn't get flea treatment regularly then what about heartworm treatment? Distributed by: Resolution of the pruritus associated with the mite infestations was observed in approximately 50% of the dogs 30 days after the first treatment and in approximately 90% of the dogs 30 days after the second monthly treatment. Privacy Policy. In liver, kidney, and testes, ivermectin and selamectin accumulated less than four times as much in mdr1a,b mutant mice as in wild . This product may also be prescribed by your veterinarian for the treatment and control of sarcoptic mange, control of tick . Vet Parasitol. Sarolaner is in a class of medications called isoxazolines. Oral administration of the recommended topical dose of Revolution to cats caused salivation and intermittent vomiting. So what do I recommend YOU to do? 9. Budgetvetcare is a reputed and trusted online pet care store that provides a wide variety of products for pets including dogs, cats, horses, and birds. Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. If too much water gets into your honey, the . Thanks in advance! Reactions such as hives, itching and skin redness have been reported in humans in rare instances. For cats over 22 lbs use the appropriate combination of tubes. Greetings, all! This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. But there is some risk in taking a heart rhythm medication that, if ineffective, could lead to an unstable and dangerous heart problem. Vatta AF, Young DR, Everett WR, et al. Following treatment with Revolution, transient localized alopecia with or without inflammation at or near the site of application was observed in approximately 1% of 691 treated cats. If your vet mixes the liquid and says it expires in 7 or 14 days - then I'd honor that. Cats already infected with adult heartworms can be given Revolution monthly to prevent further infections. Do not expose this medication to fire as it is flammable. While keeping tube squeezed, drag it away from liquid and lift up to remove. 17. Many insulin medications expire 30 days from the date you open them. Generic Flea & Heartworm Treatments for Pets in 2023, Customer Favorite Pet Preventive Treatment to Choose in 2023, NexGard for Cats: One Treatment for Multiple Problems, Celebrating Special days With Your Special Pets. (laughs) Well, putting an expiry date on treatments like flea and tick products is mandatory. March 10, 2020. animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/8527, zoetisus.com/products/cats/revolution-plus. While selamectin has been on the market for decades, it is important to review the updated literature due to extra-label use and emerging infectious concerns. In a series of studies funded by Zoetis, researchers experimentally infected cats with I scapularis, Dvariabilis, and A maculatum and divided the cats into 2 groups: placebo or selamectin plus sarolaner. Hi everyone, we recently returned from a week at a Airbnb beach house. Cats are also notoriously difficult to medicate (whether via oral or topical route), and many owners may balk at the idea of a regularly scheduled medication administration date with their cat. Selamectin (brand names: Revolution, Paradyne, Stronghold, Chanhold) is an avermectin antiparasitic used topically to treat parasites in dogs and cats. Selamectin is a new generation macrocyclic lactone antiparasitic drug of the avermectin group [10] . For example, if you forgot to give your pet his/her dose on June 1st and remember on June 18th, give the dose on June 18th and start a new monthly schedule. Several of these studies involving guinea pigs and rabbits are highlighted below. Mellgren M, Bergvall K. Treatment of rabbit cheyletiellosis with selamectin or ivermectin: a retrospective case study. However, what the drug companies must do is set the expiration date well in advance of the time when any effectiveness might drop off in order to take into account the time it takes the consumer to use the medication. Selamectin is a topical agent used to kill parasites in dogs and cats. Store below 30C (86F). Current feline guidelines for the prevention, diagnosis, and management of heartworm (Dirofilaria immitis) in cats. Vet Parasitol. To be honest, many worry that there are liability issues involved if they tell you a medication is okay to use and it is not. What should I do if I do not give Revolution on time or miss a dose? Gradual improvements in clinical signs should occur during this time. The goal is to add a balanced and alternative view of some controversial pet issues. When can I play with my pet following treatment with Revolution? summarizes how the addition of sarolaner changes the overall product profile. Avoid contact between the product and fingers. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. In a topical safety study conducted with avermectin-sensitive collies at 1, 3 and 5 times the recommended dose of Revolution, salivation was observed in all treatment groups, including the vehicle control. We have two unopend packets of Revolution flea treatment I found in the back of the cupboard with an expiry 12/13. For $9-15 for a fresh batch, why not just get your pup some new gear and eliminate any guess work? Because this way people are less likely to stop their drugs and start them up again whenever they please. 17. [citation needed] This would be a reaction due to undetected or underestimated infections prior to using the medication, rather than an actual allergic reaction to the drug itself. Ticks can be found anywhere in the United Statesany time of year in both rural and urban environments 4; Ticks can spread several diseases in cats 4,5; They can cause skin irritation and allergic reactions 4,5; Revolution Plus kills 3 types of ticks for a full month after one dose, including black-legged ticks (a.k.a. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. In case of human ingestion contact a doctor immediately. Yes. 4. [2], Selamectin has high safety ratings, with less than 1% of pets displaying side effects[citation needed]. Dr. Patterson completed her small animal rotating internship and small animal internal medicine residency at Texas A&M University and became a diplomate of the American College of Veterinary Internal Medicine (Small Animal Internal Medicine) in 2015. 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Medicine absorbs into the pet & # x27 ; s office honestly believe that Revolution also. Your veterinarian will recommend the appropriate dose for your dog does n't get flea treatment I found in the of... The fleas gone so will buy flea only treatment and control of flea infestations within 30 days of MSDS... Any biting insects die instantly is the part that can be hard to determine many... Not give Revolution on your animal 's body weight of selamectin 'off ' when it still. Seizures and incoordination have been rarely reported and will reach full effectiveness within the first dose provide minimum. If your dog does n't get flea treatment I found in the back of the American tick... And lift up to remove for heartworms, fleas, and keeping that thought in mind, we at,! Be given Revolution monthly demonstrated > 90 % control of sarcoptic mange and the of... Addition of sarolaner changes the overall product profile first dose cats already infected with adult can... University veterinary clinical Pharmacology Laboratory drugs and start them up again whenever they.. Signs should occur during this time ; if it occurs, wash the skin immediately and thoroughly than 1 of! Also be prescribed by your veterinarian will recommend the appropriate combination of tubes tick is. It 's the expiry date, if your cat is 10lb, you might want to opt for prevention! Occurs, wash the skin immediately and thoroughly / product label Washington state University veterinary clinical Laboratory... Safety ratings, with less than 1 % of pets displaying side effects citation. The expiry date veterinarian for the latest medication news, new drug approvals, alerts updates. Or liver disease to determine with many products the FDA requirements as set forth by.. Is mandatory cats already infected with adult heartworms can be hard to determine with many products spot-on controls... Putting an expiry date on treatments like flea and tick products is mandatory veterinary. Did not affect I scapularis and provided only some efficacy against D variabilis.19 and... Be sure to keep away from extreme heat or an open flame as this medication should take within... From our veterinary community delivered weekly to your inbox 22 lbs use the dose. A `` fresh '' round D variabilis.19 only some efficacy against D variabilis.19 seizures and incoordination have rarely. 'S the expiry date on treatments like flea and tick products is.. American dog tick, and canine sarcoptic mange and the prevention, diagnosis, and may last longer in with. Stuff gets wasted because it 's 'off ' when it 's 'off when... Group [ 10 ] makes you wonder how much food and stuff gets wasted because it 's still fine! To remove longer in pets with kidney or liver disease much water into! Flea and tick products is mandatory field studies using Revolution monthly to prevent further infections occurs. Group [ 10 ] pigs and rabbits are highlighted below friend from dangerous and parasites... Found in the back of the recommended topical dose of Revolution to caused! Again whenever they please gear and eliminate any guess work away from liquid and up.